Chemical Communications

Chemical Communications

NanoMIPs to fight bacterial infection in the world of decreasing effectiveness of antibiotics

We are pleased to present the first successful use of molecularly imprinted nanoparticles for the degradation of N-L-hexanoyl homoserine lactone, a Gram-negative quorum sensing autoinducer. The presented work is a promising new technology that will help to fight bacteria without the risk of developing resistance, especially in the times when the effectiveness of antibiotics has been declining dramatically.

Work is presented in Application of molecularly imprinted polymer nanoparticles for degradation of the bacterial autoinducer N-hexanoyl homoserine lactone and published in the Chemical Communications, with contributions made by Joanna Czulak from MIP Diagnostics, alongside colleagues at The University of Leicester.