nanoMIPs are versatile, robust and highly stable alternatives to antibodies.  

MIPs are prepared using a proprietary imprinting process involving the self-assembly of binding monomers around a target.

Monomers are then polymerised to generate a nanoMIP with a single binding site: a 'synthetic' antibody. Our proprietary technology includes a novel method to produce nanoMIPs which circumvents the drawbacks of traditional Molecularly Imprinted Polymer manufacturing methods. nanoMIPs have been created to small molecules, metabolites, peptides, proteins, viruses and more. Targets are not limited to those that elicit an immune response; no animals are used in the manufacture of Molecular Imprinted Polymers.

 We would be delighted to discuss how to create the best possible MIPs for you.

PURIFICATION & SEPARATIONS  The use of polymers for separation and purification is a well established process.

PURIFICATION & SEPARATIONS

The use of polymers for separation and purification is a well established process.

Purification & Separations with MIPs

For Small Molecules

The use of polymers for separation and purification is well established, especially for small molecules.

To some extent this is what the old style monolithic Molecularly Imprinted Polymers did best. At MIP Diagnostics we have made further advances with novel forms of MIPs and process to generate them. Some of our polymers have been used to purify a range of targets including: 

  • (S)-Citalopram

  • Amiodarone

  • Salbutamol

  • 4-ethyl phenol

  • (+)-(S)-desmethylcitalopram and (+)-(S)-didesmethylcitalopram

  • Melamine

We can also use nanoMIPs to enable the selective removal of sub-cellular targets such as bacteriophage or viruses from water to make drinking water safe for consumption.

If you would like more information about polymers, including nanoMIPs, for purification and separation purposes please contact us at enquiries@mip-dx.com.

SENSORS BASED ON MIPS  Our sensors can be easily tuned to target a wide range of compounds including inorganic ions and proteins.

SENSORS BASED ON MIPS

Our sensors can be easily tuned to target a wide range of compounds including inorganic ions and proteins.

Sensors Based on MIPs

Universal Sensor Platform

Sensors can be developed using MIPs as recognition elements, in order to impart selectivity towards a determined target compound.

MIPs have been integrated with a range of transducers based on electrochemical, optical, gravimetric and thermal detection methods. For sensor development nanoMIPs are advantageous, as they can be used for fabrication using existing techniques originally developed for natural receptors such as enzymes and antibodies. Also, due to their stability nanoMIPs can be dispersed in conductive inks and used directly for manufacture of screen-printed electrodes. Some of our polymers have been used to prepare sensors for targets including: 

  • Cocaine

  • Ethylphenol

  • Histamine

  • Phosphate

  • Vancomycin

  • Trypsin

  • Bacteriophages

We can also offer a universal electrochemical sensor platform for label-free detection and quantification of analytes independently of their electrochemical properties. The sensor can be easily tuned to target a wide range of compounds, from small inorganic ions up to large molecules such as proteins.

If you would like more information about our universal sensor platform, or how nanoMIPs can be used for sensor development please contact us at enquiries@mip-dx.com